Advanced Biomedical Research and Innovation

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Layasadat Khorsandi Author

LayasadatKhorsandi@gmail.com

Subjects of specialization
Adolescent and Pediatric Gynecology, Anorexia Nervosa, Biochemistry of Reproductive Science, Biodiversity Management, Biodiversity and Conservation

Affiliation
Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

Biography

Layasadat Khorsandi professor from Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran · Cell and Molecular Research Center PhD. Awards Medal “Gustavo Baz Prada” (for Bs in 1993 UNAM), Medal “Alfonso Caso” (for Ph D in 1999), and LAS/ANS award for best publication of the year in 2010 by Nuclear American Society Latinoamerican Section. International articles 115, chapters in book 20, thesis direction 41

Publications

Short Article Open Access

Generation of artificial pancreas by using MIN-6 cell line culture seeded in decellularized testis's rat scaffold

Author(s): Samaneh Karimi, Jafar Ai, Layasadat Khorsandi , Azin samimi and Afrooz karimi

Objective: Type 1 diabetes is an autoimmune disease which is due to the lack of 𝛽 cells. Regenerative medicine offers the opportunity for curing diabetes. Native extracellular matrix (ECM) creates a reconstruction platform to replace the organs. A decellularized rats testis was used as a natural 3D scaffold in this experiment. MIN_6 𝛽 cells were planted in the scaffold. Methods: The decellularized testes were prepared for in vitro analyses. Results: The decellulalarazed testes were analyzed by histological studies such as H&E and DAPI staining. SEM showed that the 3D ultra structure of the testis remained intact. In vitro studies point out that the decellularized scaffold was non_toxic and preformed a good plateform for MIN_6 𝛽 cells. The DTZ staining showed c... view more»

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