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Hindi Clinical Oncology: Case Reports
LR Nayak (India) Author
Subjects of specialization
Affiliation
oncology, cell tumour, molecular biology, cancer cells
Department of Medical Oncology, Tata Memorial Centre, Parel, Mumbai, India
Biography
Dr. LR Nayak, is working in Department of Medical Oncology, Tata Memorial Centre, Parel, Mumbai, India. Dr. Nayak has interest in the fields of oncology, cell tumour, molecular biology, cancer cells.
Publications
Case Report Open Access
Isochromosome i(9)(q10): A Rare Chromosomal Aberration in B-cell Acute Lymphoblastic Leukemia
Author(s): Yogita Rohil, Dhanlaxmi Shetty, Hasmukh Jain and LR Nayak (India)
Cytogenetic analysis in Acute Lymphoblastic Leukemia (ALL) reveals number of non-random chromosome abnormalities which play an important role in prognostication of patients. Isochromosomes are uncommonnon-random chromosome aberrations in acute lymphoblastic leukemia (ALL) and prognostic significance of the presence of isochromosome(s) remains to be well established. The incidence of i(9q) in ALL is very low. Majority of the patients are older than 10 years and the aberration occurs in combination with other chromosomal abnormalities. We present two cases of adult BALL with i(9q) as one of the cytogenetic aberration at diagnosis. Case 1 patient was given standard treatment protocol and complete remission was achieved at the end of induction phase II therapy a... view more»
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