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Hindi Journal of Nanomaterials & Molecular NanotechnologyISSN: 2324-8777
Marc Wegmann Author
Subjects of specialization
Affiliation
Reactive Oxygen Species, Silicon Nanoparticles, Oxidative Stress, Nanotechnology, Nanoparticles
Department of Chemistry and Pharmacy, Physical Chemistry I and ICMM,Friedrich-Alexander University of Erlangen-Nuremberg, Egerlandstr.3, D-91058 Erlangen, Germany
Biography
Oxidized Silicon Nanoparticles and Iron Oxide Nanoparticles for Radiation Therapy is one of his publications. He is from Department of Chemistry and Pharmacy, Physical Chemistry at CMM, Friedrich-Alexander University of Erlangen-Nuremberg, Egerlandstr.
Publications
Research Article Subscription
Oxidized Silicon Nanoparticles and Iron Oxide Nanoparticles for Radiation Therapy
Author(s): Stefanie Klein, Anja Sommer, Maria L. Dell’Arciprete, Marc Wegmann, Susanne V. Ott, Luitpold V. R. Distel, Winfried Neuhuber, Mónica C. Gonzalez, and Carola Kryschi
Oxidized Silicon Nanoparticles and Iron Oxide Nanoparticles for Radiation Therapy
Our research objective is to develop superparamagnetic iron oxide nanoparticles and silicon nanoparticles as radiosensitizers for cancer therapy. After internalization by breast tumor cells and irradiation with X-rays, the nanoparticles were observed to enhance the oxidative stress in tumor cells. While silicon nanoparticles increase the reactive oxygen species production under X-ray treatment due to their incompletely oxidized surface, positively charged amino-functionalized silicon nanoparticles enhance the formation of mitochondrial reactive oxygen species formation because of ... view more»
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