Marcelo Donizetti Chaves Author
Subjects of specialization
Affiliation
DNA Repair, Molecular Toxicology
Department of Biosciences, Federal University of S
Dr. Marcelo Donizetti Chaves, is currently working in the Department of Biosciences, Federal University of São Paulo (UNIFESP), Brazil. Marcelo Donizetti Chaves, areas of research interests include Micronucleus Tests, Comet Assay, Mutagenicity, Genotoxicity, DNA Damage, Molecular Toxicology, Cancer Biology, Genome Stability, DNA Repair etc.,
Case Report Open Access
Author(s): Marcelo Donizetti Chaves, Liciane Bello, Angela Maria Paiva Magri, Murilo C. Crovace and Ana Claudia M Renno
Periapical inflammatory lesion is one of the most prevalent diseases in general dental practices. Many consequences are related to this disease including the appearance of bone defects. In this context, treatments able of stimulating bone tissue have been developed, including osteogenic biomaterials. This pilot case study aimed to evaluate the effects of Biosilicate® in the process of healing in bone defects due to periapical disease. A 53-year-old woman, with recurrent episodes of acute exacerbation of an inflammatory chronic process in the apex of the maxillary left lateral incisor (MLLI), presenting endodontic retreatment and intracanal pin, was studied. Biosilicate® was implanted in the area of the defect and the treatment was analyzed by radiographic examinations (immediate... view more»