Maria L. Dell?Arciprete Author
Subjects of specialization
Affiliation
Nanoscience, Nanotubes, Nanomaterials, Nanotechnology, Nanoparticles.
Instituto de Investigaciones Fisicoqu
María Laura Dell'Arciprete currently works at the Departamento de Química , National University of La Plata. María does research in Nanotechnology and Photochemistry. Oxidized Silicon Nanoparticles and Iron Oxide Nanoparticles for Radiation Therapy is one of her publication
Research Article Subscription
Author(s): Stefanie Klein, Anja Sommer, Maria L. Dell’Arciprete, Marc Wegmann, Susanne V. Ott, Luitpold V. R. Distel, Winfried Neuhuber, Mónica C. Gonzalez, and Carola Kryschi
Oxidized Silicon Nanoparticles and Iron Oxide Nanoparticles for Radiation Therapy
Our research objective is to develop superparamagnetic iron oxide nanoparticles and silicon nanoparticles as radiosensitizers for cancer therapy. After internalization by breast tumor cells and irradiation with X-rays, the nanoparticles were observed to enhance the oxidative stress in tumor cells. While silicon nanoparticles increase the reactive oxygen species production under X-ray treatment due to their incompletely oxidized surface, positively charged amino-functionalized silicon nanoparticles enhance the formation of mitochondrial reactive oxygen species formation because of ... view more»