Archives of Transplantation

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Mark W Russo Author

mark.russo@carolinashealthcare.org (704) 355-6649

Subjects of specialization
internal medicine, gastroenterology, transplant hepatology

Affiliation
Division of Hepatology, and Clinical Professor of Medicine at Carolinas Medical Center-Atrium Health in Charlotte, North Carolina.

Biography

Mark Russo MD MPH FAASLD, FACG AGAF is Medical Director of Liver Transplantation, Chief, Division of Hepatology, and Clinical Professor of Medicine at Carolinas Medical Center-Atrium Health in Charlotte, North Carolina. He serves as program director for the advanced hepatology fellowship. He graduated from The Mount Sinai School of Medicine and completed his residency, gastroenterology and transplant hepatology fellowship at The University of North Carolina Hospitals in Chapel Hill. He is board certified in internal medicine, gastroenterology and transplant hepatology.

Publications

Research Article Open Access

Estimates of Glomerular Filtration Rate in Liver Transplant Recipients are not Accurate: A Role for 24-Hour Urine Creatinine Clearance

Author(s):

Mark W Russo, Krista Bossi, Gale Groseclose, David M Levi, Lon Eskind, Bennett Noell, Anderson WE, Philippe J Zamor and Vincent Casingal

Background: Kidney injury is common among liver transplant recipients. Equations estimating glomerular filtration rate were not developed in liver transplant recipients. Aim: To determine if GFR equations and 24-hour urine creatinine clearance accurately estimate GFR in liver transplant recipients. Methods: 30 subjects were enrolled within 6 months of transplant and obtained estimates of GFR. The iothalamate scan served as the gold standard and it was compared to GFR equations and 24- hour urine creatinine clearance. Results: The mean time to iothalamate scan was 110 + 50 days.The mean iothalamate GFR was 90 + 37 mL/min/1.73 m2. The GFR equations underestimated GFR with 47%-63% of estimates differing by more than 20% from the iothalamate GFR. Among the equations the CKD-EPI-Cys-Cr was t... view more»

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