Marlene Shehata Author

Editorial Open Access

Genetic Determinants of Salt- Sensitive Hypertension

Author(s):

Marlene Shehata, Fady Youssef and Alan Pater

Genetic Determinants of Salt - Sensitive Hypertension

Despite the marked advances in research on genetic determinants of salt-sensitive hypertension in human and animal models of saltsensitivity, the mechanisms underlying salt-sensitivity that is induced by high levels of salt in the diet remain unclear. While excessive dietary sodium chloride (NaCl or salt) intake is a predominant cause of hypertension, the individual blood pressure response to high salt intake is heterogeneous. The existence of interindividual variability in the genetic make-up of individuals might explain the different blood pressure responses to excessive dietary salt intake.

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DOI: 10.4172/2327-5790.1000e101

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