Maryam Akgagri Author

Research Article Open Access

Methadone Extraction by Modified QuEChERS Method in Post-mortem Samples by Gas Chromatography-Mass Spectrometry

Author(s):

Seyed Majid Salami Asl, Mohammad Javad Khodayar, Zahra Mousavi and Maryam Akgagri

Background: Extraction in the first line toxicology laboratory is the stage of analysis and diagnosis, the diagnosis process of the drug is completely dependent on the extraction method. New high-efficiency extraction methods, replace past practices. QuEChERS extraction method has already been introduced in pesticide extraction. In forensic toxicology, autopsy samples from the bodies to investigate the cause of death after extraction and analysis are interpreted by different devices.

Objective: In this paper, extraction of methadone drug substance by QuEChERS method was investigated in autopsy samples.

Method: QuEChERS extraction method an easy and fast tube method using MgSO4 and NaCl salts and ethyl acetate solvent bas... view more»

Abstract HTML PDF