Masahiro Inagaki Author

Research Article Open Access

Sitagliptin Inhibits the Lipopolysaccharide-Induced Inflammation

Author(s):

Hitomi Hasegawa, Yuya Nakamura, Mayumi Tsuji, Ran Ono, Tatsunori Oguchi, Katsuji Oguchi, Yuji Kiuchi, Isao Ohsawa, Hiromichi Gotoh, Yoshikazu Goto and Masahiro Inagaki

Sitagliptin Inhibits the Lipopolysaccharide-Induced Inflammation

Abstract

Objective: Sitagliptin is an anti-diabetic Dipeptidyl peptidase-4 (DPP-4) inhibitor; used worldwide with a well-established evidence base as an effective anti-diabetic therapy and the lowest cost of all DPP-4 inhibitors. Atherosclerosis and inflammation are more common in diabetic patients than in nondiabetic patients, and progression of atherosclerosis contributes to this infla... view more»

DOI: 10.4172/2325-9604.1000148

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