McIntyre Author
Subjects of specialization
Affiliation
Postmortem Redistribution Factor
Forensic Toxicology Laboratory Manager, County of San Diego Medical Examiner
I am McIntyre, belonging to Forensic Toxicology Laboratory Manager, County of San Diego Medical Examiner’s Office, 5570 Overland Ave, Suite 101, CA 92123, San Diego, USA, interested in the field of Postmortem Redistribution Factor.
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Author(s): McIntyre, Iain M
A “Theoretical” Postmortem Redistribution Factor (Ft) as a Marker of Postmortem Redistribution
Postmortem redistribution (PMR) refers to the changes that can occur in drug concentrations after death. Literature supports a model describing drugs with a liver (L) to peripheral blood (P) concentration (L/P) ratio less than 5 L/kg as being prone to little or no PMR, while drugs with an L/P ratio greater than 20-30 L/kg have propensity for substantial PMR. Additionally, the concept of a post-mortem redistribution (F) factor has been recently described to express the direct relationship between post mortem peripheral blood and the corresponding antemortem view more»