Journal of Nanomaterials & Molecular NanotechnologyISSN: 2324-8777

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M髇ica C. Gonzalez Author

Subjects of specialization
Fluorescence, Luminescence, Photophysics, Luminescent Materials, Dye Chemistry

Affiliation
Instituto de Investigaciones Fisicoqu

Biography

Oxidized Silicon Nanoparticles and Iron Oxide Nanoparticles for Radiation Therapy is one of her publications. She is in the Instituto de Investigaciones Fisicoqu韒icas Te髍icas y Aplicadas (INIFTA), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, Casilla de Correo 16, Sucursal, La Plata, Argentina


Publications

Research Article Subscription

Oxidized Silicon Nanoparticles and Iron Oxide Nanoparticles for Radiation Therapy

Author(s): Stefanie Klein, Anja Sommer, Maria L. Dell鈥橝rciprete, Marc Wegmann, Susanne V. Ott, Luitpold V. R. Distel, Winfried Neuhuber, M贸nica C. Gonzalez, and Carola Kryschi

Oxidized Silicon Nanoparticles and Iron Oxide Nanoparticles for Radiation Therapy

Our research objective is to develop superparamagnetic iron oxide nanoparticles and silicon nanoparticles as radiosensitizers for cancer therapy. After internalization by breast tumor cells and irradiation with X-rays, the nanoparticles were observed to enhance the oxidative stress in tumor cells. While silicon nanoparticles increase the reactive oxygen species production under X-ray treatment due to their incompletely oxidized surface, positively charged amino-functionalized silicon nanoparticles enhance the formation of mitochondrial reactive oxygen species formation because of ... view more禄

DOI: 10.4172/2324-8777.S2-002

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