M髇ica C. Gonzalez Author
Subjects of specialization
Affiliation
Fluorescence, Luminescence, Photophysics, Luminescent Materials, Dye Chemistry
Instituto de Investigaciones Fisicoqu
Oxidized Silicon Nanoparticles and Iron Oxide Nanoparticles for Radiation Therapy is one of her publications. She is in the Instituto de Investigaciones Fisicoqu韒icas Te髍icas y Aplicadas (INIFTA), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, Casilla de Correo 16, Sucursal, La Plata, Argentina
Research Article Subscription
Author(s): Stefanie Klein, Anja Sommer, Maria L. Dell鈥橝rciprete, Marc Wegmann, Susanne V. Ott, Luitpold V. R. Distel, Winfried Neuhuber, M贸nica C. Gonzalez, and Carola Kryschi
Oxidized Silicon Nanoparticles and Iron Oxide Nanoparticles for Radiation Therapy
Our research objective is to develop superparamagnetic iron oxide nanoparticles and silicon nanoparticles as radiosensitizers for cancer therapy. After internalization by breast tumor cells and irradiation with X-rays, the nanoparticles were observed to enhance the oxidative stress in tumor cells. While silicon nanoparticles increase the reactive oxygen species production under X-ray treatment due to their incompletely oxidized surface, positively charged amino-functionalized silicon nanoparticles enhance the formation of mitochondrial reactive oxygen species formation because of ... view more禄