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Hindi Journal of Nanomaterials & Molecular NanotechnologyISSN: 2324-8777
Mohd Tajudin Mohd Ali Author
Subjects of specialization
Affiliation
Drug Synthesis, Natural Product Synthesis, Natural Product Chemistry, Asymmetric Catalysis, New Drug Discovery
Faculty of Applied Sciences, Universiti Teknologi MARA (UiTM), 40450 Shah Alam, Selangor, Malaysia
Biography
Mohd Tajudin Mohd Ali working in Faculty of Applied Sciences, Universiti Teknologi MARA (UiTM), 40450 Shah Alam, Selangor, Malaysia. Mohd Tajudin Mohd Ali has an area of research interest in the field of Drug Synthesis, Natural Product Synthesis, Natural Product Chemistry, Asymmetric Catalysis, Click Chemistry, New Drug Discovery.
Publications
Research Article Subscription
Synthesis and Characterization of Betulinic Acid-Aminopropyltriethoxysilane Compounds and Their Assembly onto Nanoporous Alumina Surfaces as Potential Therapeutic Agents
Author(s): Abdul Hadi Mahmud, Abdul Mutalib Md Jani and Mohd Tajudin Mohd Ali
The present study describes the synthesizing and attaching of betulinic acid-aminopropyl triethoxysilane (BA-APTES) on top of the nanoporous alumina (NA) surface. The NA was fabricated by using electrochemical anodization process under an applied voltage of 40 V for 20 hours resulting in average pore size of 45 nm characterized by Scanning Electron Microscope (SEM). The well-recognized therapeutic compound, betulinic acid (BA) was first extracted from the bark of Melaleuca cajuputi plant and further purified by column chromatography. The purified BA was incorporated with APTES using 1-hydroxybenzotriazole hydrate (HOBt) and O-(Benzotriazol-1-yl)-N,N,N’-tetramethyluronium hexafluorophosphate (HBTU) as a peptide coupling agent. The synthesized BA-APTES was silanized on top of the fa... view more»
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