Morris H Baslow Author
Subjects of specialization
Affiliation
Magnetic Resonance Imaging
Nathan S Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
Morris H Baslow belongs to Nathan S Kline Institute for Psychiatric Research intrested in the field PKU: Phenylketonuria; BH4: Tetrahydrobiopterin; NBS: Newborn Screening; PAH: Phenylalanine Hydroxylase; MS/MS: Tandem Mass Spectrometry; Phe: Phenylalanine; MRS: Magnetic Resonance Spectroscopy; MPKUS: Maternal PKU Syndrome; MRI: Magnetic Resonance Imaging; LNAA: Large Neutral Amino Acids from 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
Research Article Subscription
Author(s): Morris H Baslow and David N Guilfoyle
Evidence that lithium Inhibits Export of N-Acetyl-L-Aspartate from Neurons: A Retrospective Study of Canavan Disease and Bipolar Disorder Patients
Lithium (Li) is an effective treatment for human bipolar disorder (BD) but whose precise mechanism and site of action are unknown. N-acetyl-L-aspartic acid (NAA) is an amino acid synthesized by and maintained at high steady-state levels within neurons from where it is exported to extracellular fluid (ECF) upon depolarization. NAA is the only precursor for N-acetylaspartylglutamate (NAAG), a neurotransmitter synthesized by neurons and also exported to ECF upon depolarization. The physiological function of NAA is as yet unclear but i... view moreĀ»