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Hindi Journal of Pharmaceutics & Drug Delivery ResearchISSN: 2325-9604
Muhammad Sajid Hamid Akash Author
Subjects of specialization
Affiliation
Ethylcellulose, Methylcellulose
Institute of Pharmacology, Toxicology and Biochemical Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University Hangzhou, China
Biography
My name is Muhammad Sajid Hamid Akash- I am from Institute of Pharmacology, Toxicology and Biochemical Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University Hangzhou, China My area of interests are Ethylcellulose
Publications
Research Article Subscription
Characterization of Ethylcellulose and Hydroxypropyl Methylcellulose Microspheres for Controlled Release of Flurbiprofen
Author(s): Muhammad Sajid Hamid Akash, Furqan Iqbal, Musa Raza,Kanwa Rehman, Shabbir Ahmed, Yasser Shahzad and Syed Nisar Hussain Shah
Characterization of Ethylcellulose and Hydroxypropyl Methylcellulose Microspheres for Controlled Release of Flurbiprofen
The objective of this study was to design and optimize polymeric microspheres of flurbiprofen (FLB) with ethylcellulose (EC) and hydroxypropyl methylcellulose (HPMC) using response surface methodology. EC and HPMC were taken as independent variables whereas; the dependent variables were % drug release at pH 1.2, 4.5 and 7.4. FTIR spectra and TGA showed no significant difference between drug and polymers. DSC and XRD studies exhibited molecular dispersion of FLB within microspheres. Contour plots were drawn to predict the relationship between dependent ... view more»
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