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Hindi Clinical Oncology: Case Reports
Nicholas Jette Author
Subjects of specialization
Affiliation
cancer, cancer oncology, Carcinogenesis, Poly(ADP-ribose) Polymerase Inhibitors
Cumming School of Medicine, University of Calgary, Calgary, Canada
Biography
Dr. Nicholas Jette is working as scientist and professor at Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA. The author has specalization in cancer, cancer oncology, chemotherapy, Carcinogenesis, Chemotherapy, Poly(ADP-ribose) Polymerase Inhibitors
Publications
Case Report Subscription
A Complete Response to Immune Checkpoint Therapy in A Treatment Refractory Patient with Metastatic Pancreatic Cancer and Mismatch Repair Deficiency
Author(s): Nicholas Jette, Adam Fundytus and Jose Monson
Abstract
Pancreatic cancer remains a difficult to treat malignancy. Advanced application of targeted chemotherapeutics has extended survival but has not resulted in cure. Recently, the application of immunotherapy has shown promise in cancers that harbour mismatch repair deficiencies and micro-satellite instability. Here, we show a metastatic pancreatic cancer with a mismatch repair deficiency respond dramatically to PD-1 inhibitor therapy.
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