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+44 28 3718 0055Journal of Genetic Disorders & Genetic ReportsISSN: 2327-5790
Noor Muhammad Author
Subjects of specialization
Affiliation
Nanocarriers
Department of Biotechnology and Genetic Engineering, Kohat University of Science and Technology, Kohat 26000, Khyber Pakhtunkhwa, Pakistan
Biography
Mr. Noor Muhammad, belongs to the department of Biotechnology and Genetic Engineering, interest in the field of Gene therapy; Cystic fibrosis; Nanocarriers; Cationic lipids; Cationic polymers, From Kohat University of Science and Technology, Kohat 26000, Khyber Pakhtunkhwa, Pakistan
Publications
Review Article Subscription
Non-Viral Vectors for Cystic Fibrosis Therapy: Recent Advances
Author(s): Faisal Qaisar, Anum Habib, Noor Muhammad and Zia ur Rehman
Gene therapy, which is the transfer of genetic materials into the cells for therapeutic purposes, holds a huge promise in treating various hereditary diseases. Gene therapy tools are currently being used for wide range of monogenic and multigenic disorders including but not limited to cystic fibrosis. Cystic fibrosis is caused due to mutations in a cystic fibrosis trans-membrane conductance regulator (CFTR) gene and therefore, works as a model disease in gene therapy field. However, an ideal delivery vehicle, that ensures both efficient intracellular delivery and subsequent sufficient expression of transgene is still lacking. Fundamentally, two types of vectors are currently used to cross various cellular barriers broadly named as viral vectors and nonviral vectors. Viral vectors, as th... view more»
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