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Hindi Journal of Pharmaceutics & Drug Delivery ResearchISSN: 2325-9604
Osmond J D Cruz Author
Subjects of specialization
Affiliation
Socio-Economic Factors
Drug Discovery Program, Department of Reproductive Biology, Paradigm Pharmaceuticals, LLC 2685 Patton Road, St. Paul, Minnesota 55113, USA,
Biography
Drug Discovery Program, Department of Reproductive Biology, Paradigm Pharmaceuticals, LLC 2685 Patton Road, St. Paul, Minnesota 55113, USA,
Publications
Review Article Open Access
Targeting Spleen Tyrosine Kinase (Syk) for Treatment of Human Disease
Author(s): Osmond J D Cruz and Fatih M Uckun
Targeting Spleen Tyrosine Kinase (Syk) for Treatment of Human Disease
Spleen tyrosine kinase (SYK) plays a crucial role in the coordination of immune recognition receptors and orchestrates multiple downstream signaling pathways in various hematopoietic cells. In addition to its well-known function in transducing Fcγ receptor- and B cell receptor-mediated events, SYK signals downstream of a growing list of immunoreceptor pathways that modulate the innate and adaptive responses.
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