Padma V Devarajan Author
Subjects of specialization
Affiliation
security implications
Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology (Elite status), N. P. Marg, Matunga (East), Mumbai 400019, India
My name is Padma V Devarajan I am from Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology (Elite status), N. P. Marg, Matunga (East), Mumbai 400019, India My area of interests are security implications
Research Article Subscription
Author(s): Rohit R Joshi and Padma V Devarajan
Anionic Self Micro-Emulsifying Drug Delivery System(SMEDDS) Of Docetaxel for Circulation Longevity
In the present study, we present anionic self microemulsifying drug delivery system (SMEDDS) of DTX for long circulation comprising of ethyl oleate, Tween-80, propylene glycol and dimethyl acetamide. The anionic charge was induced by including two different anionic surface active agents Sodium oleate and Gantrez AN-119 which localized at the oil water interface as evident by the negative zeta potential of -16mV and -26mV respectively. Hemolysis <15% exhibited by SMEDDS confirmed safety for intravenous administration. Intrav... view moreĀ»