Journal of Pharmaceutics & Drug Delivery ResearchISSN: 2325-9604

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Palanirajan Vijayaraj Kumar Author

Subjects of specialization
Cancer Cell Lines

Affiliation
Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Jalan Menara Gading, UCSI University(South Campus), Taman Connaught, Cheras 56000, Kuala Lumpur, Malaysia

Biography

My name is Palanirajan Vijayaraj Kumar-  I am from  Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Jalan Menara Gading, UCSI University(South Campus), Taman Connaught, Cheras 56000, Kuala Lumpur, Malaysia  My area of interests are  Cancer Cell Lines                               


Publications

Research Article Subscription

Enhanced Cytotoxic Effect of Chemically Conjugated Polymeric Sirolimus against HT-29 Colon Cancer and A-549 Lung Cancer Cell Lines

Author(s):

Bontha Venkata Subrahmanya Lokesh and Palanirajan Vijayaraj Kumar

Enhanced Cytotoxic Effect of Chemically Conjugated Polymeric Sirolimus against HT-29 Colon Cancer and A-549 Lung Cancer Cell Lines

Background/Aim

Sirolimus (SR) is highly protein binding drug (92%) and lipophilic (log P=4.917) in nature. It has half life of 57- 63hrs and oral bioavailability is 20% even less when after eating food rich in fat. In our objective of the study, SR is chemically conjugated with biodegradable polymers like methoxy-polyethylene glycolic acid (mPEG COOH) and Poly(... view moreĀ»

DOI: 10.4172/2325-9604.1000132

Abstract HTML PDF



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