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Hindi Clinical Oncology: Case Reports
Patel Dharmesh M Author
Subjects of specialization
Affiliation
Molecular Biology of Cancer ,Molecular Tumor Board, ,Breast Cancer ,Ovarian Cancer,Skin Cancer
Cytogenetic Lab, Department of Cancer Biology, Gujarat Cancer & Research Institute, Asarwa, Ahmedabad-380016, India
Biography
Dr. Patel dharmesh is working in Gujarat Cancer & Research Institute in a Cytogenetic Lab in the Department of Cancer Biology, Gujarat Cancer & Research Institute, Research Assistant, Gujarat
Publications
Research Article Open Access
A Sole Cytogenetic Abnormality r (2) in Acute Lymphocytic Leukemia Patient: An Indian Experience
Author(s): Patel Dharmesh M, Trivedi Pina J, Brahmbhatt Manisha M and Patel Prabhudas S* (India)
Cytogenetic abnormalities are established as important prognostic factor for Leukemia. After the first report of a ring chromosome in a case of human leukemia ring chromosomes have been infrequently (<10%) detected in hematopoietic neoplasias. However, ring chromosomes are part of complex karyotype associated with a poor prognosis. In this study we document a case of 21 years old Acute Lymphoblastic Leukemia (ALL) patient. Short term unstimulated bone marrow (BM) and peripheral blood lymphocyte cultures were performed. The karyotype report was 46, XY, r (2)(p23-25q33-37). Fluorescence in-situ hybridization using WCP for chromosome 2 confirmed presence of ring chromosome 2. In most cases, there are no confirmatory reports on an association between a specific leukemia subtypes with rin... view more»
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