Clinical Oncology: Case Reports

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Patel Prabhudas S (India) Author

Subjects of specialization
Molecular Biology of Cancer ,Thoracic Cancer,Molecular Tumor,Gastrointestinal Cancer,Ovarian Cancer

Affiliation
Cytogenetic Lab, Department of Cancer Biology, Gujarat Cancer & Research Institute, Asarwa, Ahmedabad-380016, India

Biography

I, Dr. Prabhudas S Patel, am currently working as Professor & Head of Cancer Biology Department at the world?s renowned Institute, The Gujarat Cancer & Research Institute (GCRI) (gcriindia.org). GCRI is a State Cancer Institute located in Ahmedabad (Gujarat state) and one of the largest cancer care centers of India. The Institute is an amalgamation of specialties in surgical oncology, medical oncology, radiation oncology, preventive oncology, pediatric oncology, neuro-oncology, gynec-oncology, radio-diagnosis and nuclear medicine, palliative medicine, laboratory and transfusion medicine, pathology, microbiology and other allied services.

Publications

Research Article Open Access

A Sole Cytogenetic Abnormality r (2) in Acute Lymphocytic Leukemia Patient: An Indian Experience

Author(s):

Patel Dharmesh M, Trivedi Pina J, Brahmbhatt Manisha M and Patel Prabhudas S* (India)

Cytogenetic abnormalities are established as important prognostic factor for Leukemia. After the first report of a ring chromosome in a case of human leukemia ring chromosomes have been infrequently (<10%) detected in hematopoietic neoplasias. However, ring chromosomes are part of complex karyotype associated with a poor prognosis. In this study we document a case of 21 years old Acute Lymphoblastic Leukemia (ALL) patient. Short term unstimulated bone marrow (BM) and peripheral blood lymphocyte cultures were performed. The karyotype report was 46, XY, r (2)(p23-25q33-37). Fluorescence in-situ hybridization using WCP for chromosome 2 confirmed presence of ring chromosome 2. In most cases, there are no confirmatory reports on an association between a specific leukemia subtypes with rin... view more»

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