Rohdewald PJ Author
Subjects of specialization
Affiliation
Menopause; Pycnogenol; Endothelial dysfunction; Oxidative stress
Institute of Pharmaceutical Chemistry, Westf
Rohdewald PJ is working in a Institute of Pharmaceutical Chemistry, Westfälische-Wilhelms-Universität, Münster, Twenteweg 15, D-48161 Muenster, Germany. He has published more number of articles and he has the good knowledge in Menopause; Pycnogenol; Endothelial dysfunction; Oxidative stress, Cesarean scar pregnancy; Ectopic pregnancy; Treatment.
Review Article Open Access
Author(s): Rohdewald PJ
Declining estrogen levels are connected to endothelial dysfunction and weakening of antioxidative defense. Endothelial dysfunction is linked to vasomotoric and sexual problems. Reduced synthesis of antioxidants as consequence of fading estrogen supply results in oxidative stress and promotes painful menstrual problems. In addition, psychosomatic symptoms as insomnia, depression and deficits in cognitive function are frequent. Compensation for loss of estrogen by hormone replacement therapy is problematic for some women because of adverse effects so that there is a need for a nonhormonal option for relief from menopausal symptoms.
The ability of French maritime pine bark extract (Pycnogenol®) to alleviate climacteric symptoms was tested in clinical trials with perimenopausal ... view more»