Journal of Applied Bioinformatics & Computational BiologyISSN: 2329-9533

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Sadeq Vallian Author

Subjects of specialization
Molecular Diagnosis, Cytogenetics, Genetic Counseling

Affiliation
Division of genetics, Department of Biology, Faculty of Science, University of Isfahan, Isfahan, Iran

Biography

Dr. Sadeq Vallian persude his postdoctoral fellowship in Laboratory Medicine in MD Anderson Cancer center from Texas University, USA. Dr Vallian was graduated in Medical Genetics from Kings College School of Medicine and Dentistry, London, UK. Dr Vallian is working as a full Professor of Human Moecular Genetics at University of Isfahan, Isfahan, IR Iran. Dr Sadeq Vallian Boroujeni was the founder of Isfahan genetics center in 2000. His current research includes Molecular Diagnosis, Cytogenetics, Genetic Counseling.


Publications

Research Article Subscription

A Computational Comparative study of α-Glucosidase Enzyme Divergence

Author(s):

Mohammad Hossein Mehraban, Younes Ghasemi and Sadeq Vallian

A Computational Comparative study of α-Glucosidase enzyme Divergence

α-Glucosidase (α-Gls) enzymes have a crucial role in digestion of carbohydrates and biosynthesis of glycoproteins. Theses enzymes hydrolyze terminal glycosidic bonds and release α-glucose from the substrate chain. They are found in prokaryotic cells, plants and mammalian tissues such as liver, blood and especially intestine. The last step of carbohydrate digestion is catalyzed by α-glucosidases (namely maltase-glucoamylase or MGAM in mammals) which results in liberation of glucose.

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DOI: 10.4172/2329-9533.1000116

Abstract HTML PDF



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