Advanced Biomedical Research and Innovation

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Samaneh Karimi Author

KarimiSamaneh@gmail.com

Subjects of specialization
Adolescent and Pediatric Gynecology, Anorexia Nervosa, Biochemistry of Reproductive Science, Biodiversity Management, Biodiversity and Conservation

Affiliation
Abadan faculty of Medical Sciences, Iran

Biography

Samaneh karimi has completed her PhD at the age of 32 years from Ahvaz Jundi Shpour University of medical science, Iran . she is the professor of Abadan faculty of medical science, Iran.

Publications

Short Article Open Access

Generation of artificial pancreas by using MIN-6 cell line culture seeded in decellularized testis's rat scaffold

Author(s): Samaneh Karimi, Jafar Ai, Layasadat Khorsandi , Azin samimi and Afrooz karimi

Objective: Type 1 diabetes is an autoimmune disease which is due to the lack of 𝛽 cells. Regenerative medicine offers the opportunity for curing diabetes. Native extracellular matrix (ECM) creates a reconstruction platform to replace the organs. A decellularized rats testis was used as a natural 3D scaffold in this experiment. MIN_6 𝛽 cells were planted in the scaffold. Methods: The decellularized testes were prepared for in vitro analyses. Results: The decellulalarazed testes were analyzed by histological studies such as H&E and DAPI staining. SEM showed that the 3D ultra structure of the testis remained intact. In vitro studies point out that the decellularized scaffold was non_toxic and preformed a good plateform for MIN_6 𝛽 cells. The DTZ staining showed c... view more»

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