Sameer Ahmad Malik Author

Research Article Open Access

The Cytotoxic Effect of Titanium Oxide Surface Modified Orthodontic Stainless Steel Wires

Author(s):

Sameer Ahmad Malik, Laxmikanth SM, Ramachandra CS, Shetty S and Reddy VS

Background: The fixed orthodontic mechano therapy has been associated with white spot lesions and plaque accumulation. Titanium oxide (TiO2) is a compound that possesses clinically significant anti-microbial action especially against lactobacillus and streptococci. However the safety of the TiO2 coated wires has still not been tested. In this study, we evaluated the cytotoxic effects of TiO2 coated stainless steel orthodontic wires. To assess the same, we used A549 cells as experimental cell line. Cells were categorized into 4 groups (n=6/group): cellular control group, represented by the cell growth; negative control group (stainless steel wire) positive control group (hydrogen peroxide), experimental group (titanium oxide coated stainless steel wires). The cultures we... view more»

Abstract HTML PDF