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Solomon Dadia Author
Subjects of specialization
Affiliation
Surgeon
Orthopaedic Oncology Unit, Tel Aviv Sourasky Medical Centre, Tel Aviv, Israel
Biography
Solomon Dadia Department of Cardiology, of the Tel Aviv Sourasky Medical Center, Affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Publications
Research Article Open Access
Similar 48-H Analgesic Effects of Pre Vs. Post-Operative Pregabalin in Orthopaedic Oncological Patients: A Randomised Double-Blind Placebo-Controlled Trial
Author(s): Uri Amit, Yehuda Kollender, Solomon Dadia, Shoshana Chazam, Aviram Hochstadt, Ron Flaishon and Avi A Weinbroum
Background: Pain after the excision of orthopaedic-oncologic lesions is intense, and its suppression requires unusual measures. Multimodal analgesia, the currently preferred analgesic methodology, consists of two or more drugs administered concurrently, an approach that induces better analgesia than if using a single agent. Pregabalin is an analgesia adjuvant that is increasingly administered perioperatively. Its 24-h pre- vs. 24-h post-incisional analgesic effects have never been compared in orthopaedic-oncologic patients.
Methods: We compared prospectively, double-blindly and randomly the 48-h postoperative analgesic requirements and numerical pain scores following the administration of pregabalin 150 mg twice daily b... view more»
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