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Hindi Clinical Oncology: Case Reports
Steven G. Leeds (USA) Author
Subjects of specialization
Affiliation
Genitourinary Cancer,Thoracic Cancer,Breast Cancer , Lung cancer
Department of Minimally Invasive Surgery, Baylor University Medical Center at Dallas, Texas, USA
Publications
Case Report Open Access
Squamous Cell Carcinoma of the Esophagus after Adalimumab Treatment for Psoriatic Arthritis from Human Papillomavirus Activation
Author(s): Suraj Sulhan, Vani Konda, Shannon Kelley, Estrellita Ontiveros and Steven G. Leeds* (USA)
Background: Human Papillomavirus (HPV) is a risk factor that can lead to the development of squamous dysplastic changes and squamous cell carcinoma in patients with coexisting immunosuppression. Such altered immune systems are seen in patients receiving anti-tumor necrosis factor agents for the treatment of various rheumatological disorders. Case presentation: Here we present the case of a 39-year-old female, non-drinker, non-smoker, with the diagnosis of psoriatic arthritis, who presented with new onset dysphagia. Her evaluation showed evidence of pan-esophageal high grade squamous dysplasia. The patient failed organ sparing endoscopic intervention with radiofrequency ablation and cryoablation warranting a near total esophagectomy. Conclusion: In an otherwise low risk patient, this ext... view more»