Sudarsanam D Author

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Anticarcinogenic Effects of Selected Alkaloids Identified from Cyperus Rotundus: An In Silico Perspective

Author(s):

Lydia J and Sudarsanam D

Anticarcinogenic Effects of Selected Alkaloids Identified from Cyperus Rotundus: An In Silico Perspective

Cyperus rotundus Linn, commonly referred to as nut grass or purple nut sedge, is a perennial grass distributed widely in the warmer parts of the world. Various parts of the plant are being used as traditional remedies for diverse aliments. Five alkaloids identified from the ethanolic extract were modelled and docked with the emerging anticancer drug target, DNA polymerase β, which fill gaps during the repair of damaged DNA. The ADME properties of the alkaloids were also analysed and compared with that of Cytarabine. Two potential inhibitors of view more»

DOI: 10.4172/2329-9533.1000122

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