Uthaisang-Tanechpongtamb W Author
Subjects of specialization
Affiliation
Medical Technology
Department of Biochemistry, Faculty of Medicine, Srinakarinwirot University, Bangkok-10110, Thailand
My name is Uthaisang-Tanechpongtamb W- Iam from Department of Biochemistry, Faculty of Medicine, Srinakarinwirot University, Bangkok-10110, Thailand My area of Interests sir Medical Technology
Research Article Open Access
Author(s): Jarintanan F, Jongrungruangchok S and Uthaisang-Tanechpongtamb W
Colon cancer is the most common cancer worldwide. Recently, natural products have been used for the treatment of cancer are becoming an important research area for drug discovery. Terrein, a fungal metabolite derived from Aspergillus terreus, has shown to have a variety of biological activities that exhibit selective anticancer activity including colon cancer. However, cytotoxic effects of terrrein against human colon cancer cell lines have never been studied before. Therefore, the present study observed the cytotoxic effects of terrein by using the MTT assay. The sensitivity was evaluated by comparing the effect to COLO 205 cells with vero cells for 24 h. The results of MTT assay showed that terrein was cytotoxic to COLO 205 with IC50 at 0.05 mM, but not to normal Vero epithel... view moreĀ»