Journal of Pharmaceutics & Drug Delivery ResearchISSN: 2325-9604

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Uthaisang-Tanechpongtamb W Author

Subjects of specialization
Medical Technology

Affiliation
Department of Biochemistry, Faculty of Medicine, Srinakarinwirot University, Bangkok-10110, Thailand

Biography

My name is   Uthaisang-Tanechpongtamb W- Iam from  Department of Biochemistry, Faculty of Medicine, Srinakarinwirot University, Bangkok-10110, Thailand  My area of Interests sir  Medical Technology                                         


Publications

Research Article Open Access

Terrein from Aspergillus terreus Induced Cytotoxic and Nuclear Changes on Human Colon Cancer COLO205 Cells

Author(s):

Jarintanan F, Jongrungruangchok S and Uthaisang-Tanechpongtamb W

Colon cancer is the most common cancer worldwide. Recently, natural products have been used for the treatment of cancer are becoming an important research area for drug discovery. Terrein, a fungal metabolite derived from Aspergillus terreus, has shown to have a variety of biological activities that exhibit selective anticancer activity including colon cancer. However, cytotoxic effects of terrrein against human colon cancer cell lines have never been studied before. Therefore, the present study observed the cytotoxic effects of terrein by using the MTT assay. The sensitivity was evaluated by comparing the effect to COLO 205 cells with vero cells for 24 h. The results of MTT assay showed that terrein was cytotoxic to COLO 205 with IC50 at 0.05 mM, but not to normal Vero epithel... view moreĀ»

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