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Hindi Journal of Applied Bioinformatics & Computational BiologyISSN: 2329-9533
Valery Kirzhner Author
Subjects of specialization
Affiliation
Population Dynamics, Bioinformatics, Computational Biology
Institute of Evolution, University of Haifa, Haifa 31905, Israel
Biography
Valery Kirzhner IS Currently working in the Department of Evolutionary and Environmental Biology Israel. He worked in the Field of study onEvolution of probability distribution in general population scheme in Mathematical Institute of the Acad. of Sci. of the USSR. His current project includes exploring the human genome sequence organization and the associations between organizational features and gene. His current research intersts includes Population Dynamics, Bioinformatics and Computational Biology.
Publications
Research Article Open Access
Testing the Metagenome Composition by the Method of Sequential Set of Primers
Author(s): Valery Kirzhner, Zeev Volkovich, Renata Avros and Elena Ravve
Metagenome is a mixture of different genomes and the analysis of its composition is, currently, a challenging problem of bioinformatics. In the present study, we attempt to solve this problem using DNAmarker primers-short nucleic acid fragments. Formally speaking, each primer maps a genome into a finite set of integral numbers. This set is called the genome spectrum for the given primer and is unique for each genome. The union of the genetic material of two genomes is mapped into the union of their spectra. Thus the metagenome spectrum always includes (covers) the spectra of the constituting genomes. A genome whose spectrum is not covered by the metagenome one, cannot be part of the metagenome, while the spectrum of a genome that is not included in the metagenome can accidentally be cov... view more»
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