Vandana Tiwari Author

Conference Proceeding Open Access

Effect of long term valproate and oxcarbazepine therapy on asymmetric dimethyl arginine and homocysteine levels in newly diagnosed epileptic children

Author(s):

Vandana Tiwari

Effect of long term valproate and oxcarbazepine therapy on asymmetric dimethyl arginine and homocysteine levels in newly diagnosed epileptic children

Abstract

Epilepsy is a central nervous system disorder with abnormal brain activity, causing seizures or unusual behavior, sensations, and loss of awareness. The present study aimed to evaluate the effect of valproate and oxcarbazepine therapy in newly diagnosed epileptic children. Changes in serum asymmetric dimethyl arginine (ADMA), homocysteine (HCY), folate and B12 levels were assessed as possible markers of cardiovascular risk and correlation between HCY and ADMA levels was ascertained. Two hundred drug naïve newly diagnosed patients with epilepsy, age seven-17 years with no k... view more»

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