Venkat Ramana Author

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Development and Comparative Assessment of Hydrocolloid Based Against Wax Based Gastro Retentive Bilayered Floating Tablet Designs of Atorvastatin Calcium Using Qbd Approach

Author(s):

Arunkanth Krishnakumar Nair, Venkat Bhaskar Rao, Useni Reddy Mallu, Venkat Ramana and Bapatu Hanimi Reddy

Development and Comparative Assessment of Hydrocolloid Based Against Wax Based Gastro Retentive Bilayered Floating Tablet Designs of Atorvastatin Calcium Using Qbd Approach

Atorvastatin calcium is one of the most widely prescribed lipid lowering drug and due to its acidic degradation properties the bioavailability reported is only 12-14% when administered orally. The gastro retentive floating tablets of Atorvastatin calcium had shown enhanced bioavailability compared to conventional immediate release dosage forms. The study presented here was focused on comparing the physicochemical properties of two different bilayered controlled release gastro retentive buoyant formu... view more»

DOI: 10.4172/2325-9604.1000137

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