Advanced Biomedical Research and Innovation

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Wang Zhangting Author

Subjects of specialization
Applied Microbiology, Applied Microscopy, Applied Mycology, Applied Physiology, Biomedical Research

Affiliation
The Chinese University of Hong Kong, Hong Kong

Biography

Wang Zhangting was working as a Research Assistant Professor, Dept of Physics Employment in Hong Kong University of Science and Technology: Hong Kong.He was completed phD from The Chinese University of Hong Kong.


Publications

Short Communication Open Access

Elucidating the bone developmental defect in Werner Syndrome using stem cells

Author(s):

Tian Yuyao, Miu Kai-Kei, Wang Zhangting and Chan Wai Yee

Werner Syndrome (WS) is an autosomal recessive genetic disorder characterized by premature aging. This disease is caused by mutations in the WRN gene. The first sign of WS is short stature. Individuals with WS have an abnormally slow growth rate, and growth stops at puberty. As a result, affected individuals have short stature. However, the mechanism is still not clear. To find out the cause of short stature in WS, the author reprogrammed the WS patients’ fibroblasts and the isogenic normal control into mesenchymal stem cells and compared the transcriptome by RNA-Seq.

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Abstract PDF



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