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Hindi Clinical Oncology: Case Reports
Warren Brenner (USA) Author
Subjects of specialization
Affiliation
Hematology and Oncology, Medical Oncology
Center for Hematology and Oncology, Lynn Cancer Institute, Boca Raton, Florida, United States
Biography
Dr. Warren Brenner has been working as a Professor at Center for Hematology and Oncology, Lynn Cancer Institute, Boca Raton, Florida, United States. He has specialized in the field of Hematology and Oncology, Medical Oncology
Publications
Case Report Open Access
Pancreatic Extraskeletal Ewing Sarcoma/Primitive Neuroectodermal Tumor: Case Report of a Rare Pathology
Author(s): Jasmine L Martin*, Heather N Swedberg, Evita Henderson- Jackson, Kun Jiang, Damon R Reed and Warren Brenner (USA)
Ewing sarcoma, characterized by an 11:22 translocation, commonly occurs in bone and soft tissue sites. We present a patient with a history of both chest wall desmoid tumor and a subsequent adenosquamous pancreatic cancer treated with distal pancreatectomy, adjuvant chemotherapy, and radiation. Two years later the patient developed lymphadenopathy, which was biopsied and sent for the tissue of origin testing. Results revealed a sarcoma with 90% certainty, primitive neuroectodermal tumor subtype. The original pancreatic tumor was sent for next-generation sequencing, which revealed an EWSR1/FLI1 fusion as the sole genetic mutation suggestive of an underlying Ewing sarcoma. Additionally, the same fusion gene was detected on the supraclavicular lymph node biopsy.... view more»
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