Winfried Neuhuber Author
Subjects of specialization
Affiliation
Nanoscience, Nanotubes, Nanomaterials, Nanotechnology, Nanoparticles.
Department of Anatomy, Chair of Anatomy I, Friedrich-Alexander University of Erlangen-Nuremberg, Krankenhausstr. 9, D-91054 Erlangen, Germany
Winfried Neuhuber is in the Department of Anatomy, Chair of Anatomy from Friedrich-Alexander University of Erlangen-Nuremberg, Krankenhausstr. 9, D-91054 Erlangen, Germany. Nano conductivity, Nanomaterials are some of the main research areas of Winfried Neuhuber.
Research Article Subscription
Author(s): Stefanie Klein, Anja Sommer, Maria L. Dell’Arciprete, Marc Wegmann, Susanne V. Ott, Luitpold V. R. Distel, Winfried Neuhuber, Mónica C. Gonzalez, and Carola Kryschi
Oxidized Silicon Nanoparticles and Iron Oxide Nanoparticles for Radiation Therapy
Our research objective is to develop superparamagnetic iron oxide nanoparticles and silicon nanoparticles as radiosensitizers for cancer therapy. After internalization by breast tumor cells and irradiation with X-rays, the nanoparticles were observed to enhance the oxidative stress in tumor cells. While silicon nanoparticles increase the reactive oxygen species production under X-ray treatment due to their incompletely oxidized surface, positively charged amino-functionalized silicon nanoparticles enhance the formation of mitochondrial reactive oxygen species formation because of ... view more»