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Hindi Clinical Oncology: Case Reports
Yogita Rohil Author
Subjects of specialization
Affiliation
B-cell Acute Lymphoblastic Leukemia, B-cell Acute Lymphoblastic Leukemia; ,FISH;, Isochromosome
Department of Cancer Cytogenetics, Advanced Centre for Training, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai, India
Biography
Dr. Yogita Rohil, is working in the Department of Cancer Cytogenetics, Advanced Centre for Training, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai, India. Her research interest in the field of B-cell Acute Lymphoblastic Leukemia; FISH; Isochromosome
Publications
Case Report Open Access
Isochromosome i(9)(q10): A Rare Chromosomal Aberration in B-cell Acute Lymphoblastic Leukemia
Author(s): Yogita Rohil, Dhanlaxmi Shetty, Hasmukh Jain and LR Nayak (India)
Cytogenetic analysis in Acute Lymphoblastic Leukemia (ALL) reveals number of non-random chromosome abnormalities which play an important role in prognostication of patients. Isochromosomes are uncommonnon-random chromosome aberrations in acute lymphoblastic leukemia (ALL) and prognostic significance of the presence of isochromosome(s) remains to be well established. The incidence of i(9q) in ALL is very low. Majority of the patients are older than 10 years and the aberration occurs in combination with other chromosomal abnormalities. We present two cases of adult BALL with i(9q) as one of the cytogenetic aberration at diagnosis. Case 1 patient was given standard treatment protocol and complete remission was achieved at the end of induction phase II therapy a... view more»
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