Journal of Immunological Techniques & Infectious Diseases ISSN: 2329-9541

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Research Article, J Immunol Tech Infect Dis Vol: 2 Issue: 3

Identification of Unique Volatile Compounds of Aspergillus fumigatus for Potential Diagnostic Breath Test by HS-SPME and GC-MS

Jian-Cong Lin, Ming Li, Wen-Ming Xu, Bo Peng, Ze-Long Guo, Wei Shui, Yan-li Xin and Chang-Ran Zhang*
Huang Pu Hospital of the First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510700, China
Corresponding author : Chang-Ran Zhang
Huang Pu Hospital of the First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510700, China
Tel: 86-20-82379627; Fax: 86-20-82376480
E-mail: [email protected]
Received: June 17, 2013 Accepted: August 05, 2013 Published: August 09, 2013
Citation: Lin JC, Li M, Xu WM, Peng B, Guo ZL, et al. (2013) Identification of Unique Volatile Compounds of Aspergillus fumigatus for Potential Diagnostic Breath Test by HSSPME and GC-MS. J Immunol Tech Infect Dis 2:3. doi:10.4172/2329-9541.1000112

Abstract

Identification of Unique Volatile Compounds of Aspergillus fumigatus for Potential Diagnostic Breath Test by HS-SPME and GC-MS

The 13/14C-urea breath test has been used in the diagnosis of gastric helicobacter pylori. The use of breath tests for diagnosis has been applied over the last 20 years. However, its applicability for diagnosis of pulmonary fungus infection was less studied. In this study, Aspergillus fumigatus-specific volatile compounds were qualitatively analyzed by headspace solid phase microextraction (HS-SPME) and gas chromatography/mass spectrometry (GC/MS).

Keywords: Aspergillus fumigatus; Headspace solid phase microextraction; Gas chromatography-mass spectrometry; Volatile organic compounds (VOCs); Breath test

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