About the Journal
Genetics and Proteomics research has grown at a bewildering pace in the past 15 years. The techniques of these fields are being applied to a wealth of biological questions and experimental systems. Journal of Genes and Proteins (JGP) is an international, peer-reviewed subscription journal reflects the full breadth and interdisciplinary nature of this research supported by proteomics observations across all kingdoms of life.
The mission of Journal is to foster the development and applications of proteomics in both basic and translational research.Our emphasis is on studies of broad interest that provide significant insight into a biological process
Journal of Genes and Proteins majorly focuses on:
- Population genetics
- Protein Structure and Function
- Chromosome biology
- DNA Organization, Replication & Evolution
- Human Genetics
- Molecular Biology
- Gene Expression
- Comparative and functional genomics
- Functional and Medicinal Genomics
- Computational Genomics
- Molecular Evolution
- Molecular Pathology
- Genetic Engineering
The scope of journal is not restricted only for genes and proteins; works related to molecular genetics, protein science and translation medicine are equally welcome. It is a boon for researchers and students to enhance the latest trends in field of genetics and proteins for improvement of public health. The Journal follows quality double blind peer review process and online manuscript submission, tracking system. Review processing is performed by the editorial board members of Journal of Genes and Proteins or outside experts; at least two independent reviewers approval followed by editor approval is required for acceptance of any citable manuscript. Authors may submit manuscripts and track their progress through the online tracking system.
It is defined as the group of proteins expressed in a specific cell at particular conditions.The techniques in proteomics involved in the global screening of complex samples in proteins and provide evidence of altered protein expression in quantitative and qualitative fields.
It is the study of changes in organisms caused by potentially heritable modifications in gene expression that does not involve changes to the underlying DNA sequence (means change in phenotype without a modifications in genotype). Epigenetic modifications can manifest in cells which terminally differentiate to end up as skin cells, liver cells and brain cells or can have more damaging effects that can result in diseases like cancer.
Molecular diagnostics is a troupe of techniques used to detect biological markers in the genome and proteome. The individual cells how express their genes as proteins by applying molecular biology to medical testing. The technique is used to diagnose disease and to decide which therapies could work best for individual patients.
It is the scientific study of chemical process involving in metabolites. Metabolomics is the systematic study of the unique chemical fingerprints that specific cellular processes leave behind and study of their small molecule metabolite profiles.
Biochemistry of Metabolism
The process that occurring within a cell. Metabolic pathways consist of anabolism-reduction synthesis of molecules and catabolism –oxidative degradation of molecules. The term metabolism is used to refer the breakdown of food and transformation into energy.
It is a part of any communication that process basic activities of cell and coordinates to all cells activity. The capability of cells to receive and response to their surroundings in the basis of development, tissue repair and immunity. The error in signaling interactions and cellular information processing are responsible for disease such as cancer and diabetes.
Molecular genetics that studies the structure and function of genes at a molecular level and apply the methods of both molecular biology and genetics. The study of chromosomes and gene expression of any organism can give awareness into heredity, genetic variation and mutations.
A vector refers to a plasmid that is engineered to make it as more useful tool for molecular biologists (all vectors are plasmids, but not all plasmids are vectors). Vectors are designed for a variety of applications including easy cloning of foreign DNA and easy expression of foreign proteins.
Metabolic syndrome that includes condition like increased blood pressure, high blood sugar, and excess body fat and excess cholesterol occurs together by increasing your risk of heart disease, strokes and diabetes.
Nutrient Gene Interactions
Nutrigenomics is the study of the effects of foods and their constituents on gene expression. This concludes that the research focusing on identifying and recognising molecular level interaction between nutrient and other dietary substances with the genome.
Gene Amplification is also called as gene duplication or DNA duplication. It is defined as the cellular process in which replicated copies of a gene are produced. This results in amplification of the phenotype or associated with the gene.
Cloning and Expression
Cloning is process to express specific proteins in vitro in order to know genes and gene manipulation effects. The process begins with cloning a gene of interest into a plasmid that contains the necessary elements for propagating the gene of interest in organisms and later expressing the gene of interest in either prokaryotic or eukaryotic cells.
Transcription is the process of copying out the DNA sequence of a gene in the similar alphabet of RNA by the enzyme RNA polymerase. Transcription is the first step in gene expression of which information from a gene is used to construct a functional product called as a protein.
In molecular biology and genetics the translation is a process in which ribosomes in a cell cytoplasm form a proteins and following transcription of DNA to RNA in the cell nucleus.
A plasmid is defined as an extra chromosomal DNA molecule found in bacteria. Plasmids and DNA are replicated using the same enzymes, but plasmids are duplicated and inherited independently from the bacterial DNA. Normally a bacterium will have only one copy of its DNA but it can have multiple copies of a plasmid.