Journal of Otology & RhinologyISSN: 2324-8785

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Case Report, J Otol Rhinol Vol: 3 Issue: 5

Malignant Transformation of Nasal Polyposis: Case Report and Review of the Literature

Guillaume Michel1*, Florent Espitalier1, Elisabeth Cassagnau2 and Olivier Malard3
1Department of Otolaryngology, University Hospital of Nantes, Nantes, France
2Department of Anatomopathology, University Hospital of Nantes, Nantes, France
3Department of Otolaryngology, University Hospital of Nantes, Nantes, France
Corresponding author : Guillaume Michel
Service d'ORL et de chirurgie cervicofaciale, CHU Hôtel Dieu, 1, Place A. Ricordeau, BP 1005, 44093 Nantes Cedex 01,
Tel: 0240083475; Fax: 0240083477
E-mail: [email protected]
Received: June 19, 2014 Accepted: August 08, 2014 Published: August 18, 2014
Citation: Michel G, Espitalier F, Cassagnau E, Malard O (2014) Malignant Transformation of Nasal Polyposis: Case Report and Review of the Literature. J Otol Rhinol 3:4. doi:10.4172/2324-8785.1000176

Abstract

Malignant Transformation of Nasal Polyposis: Case Report and Review of the Literature

Nasal polyposis is a chronic inflammatory disease of the nasal mucosa. Nasal polyps are bilateral and benign, and characterized in histopathological terms by epithelial and vascular remodelling as well as the presence of an inflammatory infiltration of the stroma. We review the literature after reporting a case of evolved nasal polyposis, with multiple in situ epidermoid carcinomas inside the inflammatory polyps. After surgical treatment, the histopathological examination revealed complete squamous metaplasia over large territories on both sides, without inverted papilloma. This was a multifocal degeneration of evolved nasal polyposis.

Keywords: Nasal Polyps; Nasal Mucosa; Nasal Obstruction; Ethmoid Sinus

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