Journal of Immunological Techniques & Infectious Diseases ISSN: 2329-9541

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Commentary, J Immunol Tech Infect Dis Vol: 2 Issue: 1

Pathogenesis of Dengue Thrombocytopenia: Prospective Challenges for Researchers

Subhash C Arya* and Nirmala Agarwal
Sant Parmanand Hospital, Delhi, India
Corresponding author : Dr. Subhash C Arya
Sant Parmanand Hospital, Delhi-110054, India
E-mail: subhashbhapaji@gmail.com
Received: December 14, 2012 Accepted: January 21, 2013 Published: January 25, 2013
Citation: Arya SC, Agarwal N (2013) Pathogenesis of Dengue Thrombocytopenia: Prospective Challenges for Researchers. J Immunol Tech Infect Dis 2:1. doi:10.4172/2329-9541.1000104

Abstract

Pathogenesis of Dengue Thrombocytopenia: Prospective Challenges for Researchers

The incidence of dengue has grown dramatically around the world in recent decades. Over 2.5 billion people – over 40% of the world’s population – are now at risk from dengue. WHO currently estimates there may be 50-100 million dengue infections worldwide every year. Dengue Haemorrhagic Fever (DHF) affects most Asian and Latin American countries and has become a leading cause of hospitalization and death among children in these regions. There continues to be little emphasis on fundamental research on the genetic susceptibility of the host, pathogenesis of Dengue virus (DENV) associated thrombocytopenia, bleeding and plasma leakage.

Keywords: Dengue; Pathogenesis; Thrombocytopenia; Host factors; Electron microscopy; Future research

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