Journal of Immunological Techniques & Infectious Diseases ISSN: 2329-9541

Research Article, J Immunol Tech Infect Dis Vol: 5 Issue: 2

Endogenous Reactivation and Exogenous Re-infection by Beijing Clade Isolated from Pulmonary Tuberculosis Patients in Sikkim, India

Gurmey K, Devi RK, Adhikari L, Narain K, Mahanta J and Singh TS*
Department of Microbiology, Sikkim Manipal Institute of Medical Sciences (SMIMS) Gangtok, Sikkim-737 102, India
Corresponding author : T Shanti kumar Singh
Department of Microbiology, Sikkim Manipal Institute of Medical Sciences (SMIMS) Gangtok, Sikkim-737 102, India
E-mail: [email protected]
Received: November 24, 2015 Accepted: April 04, 2016 Published: April 18, 2016
Citation: Gurmey K, Devi RK, Adhikari L, Narain K, Mahanta J, et al. (2016) Endogenous Reactivation and Exogenous Re-infection by Beijing Clade Isolated from Pulmonary Tuberculosis Patients in Sikkim, India. J Immunol Tech Infect Dis 5:2. doi:10.4172/2329-9541.1000141

Abstract

Endogenous Reactivation and Exogenous Re-infection by Beijing Clade Isolated from Pulmonary Tuberculosis Patients in Sikkim, India

The ascending rate of retreatment of tuberculosis in Sikkim, India is becoming a key issue due to default, relapse and failure. However, in case of relapse and failure, clinician wants to confirm whether they are fighting same bacteria during retreatment to choose the drugs during second spell of treatment. We wanted to confirm the bacterial strain homology isolated in both occasions (primary isolate and the isolated after relapse or failure) using molecular tools.

Keywords: Relapse; Failure; Endogenous reactivation; Exogenous reinfection; Beijing strain; Drug resistance

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