Journal of Pharmaceutics & Drug Delivery Research ISSN: 2325-9604

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Research Article, J Pharm Drug Deliv Res Vol: 4 Issue: 4

Physicochemical Properties of Co-Precipitate of Plantain Peel Cellulose and Gelatin

Orji JI, Akpa PA and Adikwu MU*
Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, University of Nsukka, Nigeria
Corresponding author : Adikwu MU
Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka and currently Vice Chancellor, University of Abuja, Abuja, Federal Capital Territory, Nigeria
Tel:
234 803 193 4708
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[email protected]
Received: September 17, 2015 Accepted: December 21, 2015 Published: December 24, 2015
Citation: Orji JI, Akpa PA, Adikwu MU (2015) Physicochemical Properties of Co-Precipitate of Plantain Peel Cellulose and Gelatin. J Pharm Drug Deliv Res 4:4. doi:10.4172/2325-9604.1000141

Abstract

Physicochemical Properties of Co-Precipitate of Plantain Peel Cellulose and Gelatin

Abstract

Cellulose was obtained from plantain peel by the soda pulping and the yield was 8%. The gelatin and cellulose were mixed in proportion of 1:1, 1:2 and 1:4. Avicel PH 101 was the standard. In this study, the compressibility%, hausner quotient and angle of repose for 1:1 was 13.5%, 1.16, 32° respectively while for 1:2 it was 17.6%, 1.21 and 38° respectively and 1:4 was 24.4%, 1.32 and 42° respectively. Avicel PH 101 had compressibility 37.1%, Hausner quotient 1.59 and angle of repose 60°. This means that 1:1 had a good flow, 1:2 had a fair flow and 1:4 had a passable flow and Avicel PH 101 had a very poor flow. The % solubility for 1:1, 1:2, 1:4 and Avicel PH 101 were 55.17%, 49.31%, 25.8% and10.98% respectively. The viscosity value for 1:1, 1:2, 1:4 and Avicel PH 101 is 8.257mpas, 6.738mpas, 5.146mpas and 4.622mpas respectively. From the values above, Avicel had the lowest % solubility, viscosity and poor flow while 1:1 had the highest % solubility, viscosity and good flow properties than others which mean that gelatin improved those properties.

Keywords: Evaluation; Co-precipitate; Plantain peel cellulose; Gelatin

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