Clinical Oncology: Case Reports

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Case Report, Clin Oncol Case Rep Vol: 4 Issue: 8

When the Little Dreams Become Huge Nightmares : A Case Report of a Huge Adrenocortical Carcinoma

Makram Khoury1*, Rhéa Akel2, Léa Khoury3, Viviane Trak Smayra3, and Fady Nasr1

1Department of Hematology-Oncology, Faculty of Medicine, Saint Joseph University, Hôtel Dieu de France Hospital, Beirut, Lebanon

2Department of Radiology, Faculty of Medicine, Saint Joseph University, Hôtel Dieu de France Hospital, Beirut, Lebanon

3Department of Pathology, Faculty of Medicine, Saint Joseph University, Hôtel Dieu de France Hospital, Beirut, Lebanon.

*Corresponding Author : Makram Khoury
Department of Hematology-Oncology, Faculty of Medicine
Saint Joseph University, Hôtel Dieu de France Hospital, Beirut, Lebanon E-mail: [email protected]

Received: July 05, 2021 Accepted: August 11, 2021 Published: August 30, 2021

Citation: Khoury M, Akel R, Khoury L, Smayra VT, Nasr F. (2021) When the Little Dreams Become Huge Nightmares : A Case Report of a Huge Adrenocortical Carcinoma. Clin Oncol Case Rep 4:8.

Abstract

Background: Adrenocortical carcinoma is a very rare and aggressive tumor of the adrenal gland. It has a poor prognosis even in the form of localized disease. It presents mainly with signs of hormonal excess but it can present with metastases.

Case presentation: We report the case of a young woman who presented a Cushing syndrome with virilization. The clinical presentation, the biochemical tests, the imaging findings and the pathology studies altogether establish the diagnosis of a huge adrenocortical carcinoma at advanced stage with identified pulmonary lesions. The patient was started on mitotane and has received chemotherapy.

Conclusion: This case is presented because of its rarity, and to highlight the importance of combining the different aspects of the presentation mode of the disease in order to establish the diagnosis.

Keywords: Adrenocortical carcinoma; Cushing; Virilization; Mitotane

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