Efficacy of Photobiomodulation Therapy in Reducing Oral Mucositis Severity in Cancer Patients Undergoing Radiotherapy

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Carlos Mendez

National Autonomous University of Mexico, Mexico

: Dent Health Curr Res

Abstract

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Oral mucositis is a common and debilitating side effect of radiotherapy in head and neck cancer patients. Photobiomodulation therapy (PBMT), using low-level laser light, has emerged as a non invasive intervention to mitigate mucosal damage and accelerate healing. This randomized controlled trial involved 60 patients undergoing radiotherapy, divided into PBMT and control groups. The PBMT group received daily laser therapy sessions targeting oral mucosal sites. Outcomes were measured by mucositis grading scales, pain scores, and quality of life indices over 6 weeks. PBMT patients exhibited significantly lower mucositis severity, with 40% experiencing only mild symptoms compared to 15% in controls. Pain reduction was also notable, with mean pain scores decreasing by 60% in the intervention group. Moreover, PBMT was well tolerated with no adverse events reported. These findings underscore PBMT as a valuable adjunct therapy for oral mucositis management, improving patient comfort and potentially allowing uninterrupted cancer treatment. Integration into oncology supportive care protocols is recommended.

Biography

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Carlos Mendezâ??s research focuses on oral complications of cancer therapies and innovative therapeutic approaches. He has led multiple clinical trials investigating laser therapies and is a recognized expert in oral mucosal diseases. Mendez contributes regularly to international guidelines on managing oral toxicities in oncology.