Journal of Immunological Techniques & Infectious Diseases ISSN: 2329-9541

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Review Article, J Immunol Tech Infect Dis Vol: 2 Issue: 1

RNA Interference: A Recent Approach for the Remedy of Various Diseases

Urkude Vikas*, Shrivastava Rahul, Mishra Amit, Yadav Mahavir and Tiwari Archana
School of Biotechnology, Rajiv Gandhi Proudyogiki Vishwavidyalaya, State Technological University of Madhya Pradesh, Bhopal (M.P), India
Corresponding author : Urkude Vikas
School of Biotechnology, Rajiv Gandhi Proudyogiki Vishwavidyalaya, State Technological University of Madhya Pradesh, Airport Bypass Road, Bhopal-462033, India
Tel: 0755742006; Fax: 0755267883
E-mail: [email protected]
Received: January 05, 2013 Accepted: March 13, 2013 Published: March 19, 2013
Citation: Vikas U, Rahul S, Amit M, Mahavir Y, Archana T (2013) RNA Interference: A Recent Approach for the Remedy of Various Diseases. J Immunol Tech Infect Dis 2:1. doi:10.4172/2329-9541.1000105

Abstract

RNA Interference: A Recent Approach for the Remedy of Various Diseases

RNA interference (RNAi) has been a recently discovered phenomenon for the analysis of regulation of gene expression in a variety of cells, by which target messenger RNA (mRNA) is cleaved by small interfering complementary RNA (siRNA). The technique is now established in in-vitrosystems, and much work is focussed on adapting RNAi for in vivoapplication. This technology may also be used for therapeutic purposes, functional genomics and target validation. This review will describe the basic biological processes that drive RNAi, indicate current approaches for the treatment of various diseases, and forecast future areas of development.

Keywords: Gene silencing; RNA interference; siRNA

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