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Hindi Journal of Pharmaceutical Sciences & Emerging DrugsISSN: 2380-9477
Aroonsri Priprem Author
Subjects of specialization
Affiliation
Pharmacology, Pharmaceutical Sciences, Medicinal Chemistry, Drag reduction, Drug Therapy
Department of Pharmaceutical Technology, Khon Kaen University, Khon Kaen, 40002, Thailand.
Biography
Aroonsri Priprem; Department of Pharmaceutical Technology, Khon Kaen University, Khon Kaen, 40002, Thailand. He stated that, "Zanthoxylum limonella Alston seed is widely distributed in the north part of Thailand. It has been traditionally used as the food ingredient and folk medicine various purpose, including stomach ache, toothache, intestinal worms, rheumatism, scabies, snake bites, fever and cholera."
Publications
Research Article Open Access
Development of Topical Oral Anti-Inflammatory Gel Containing Zanthoxylum limonella seed Extracted: A Preclinical Study
Author(s): Aroonsri Priprem, Sucharat Limsitthichaikoon, Kouichi Nakagawa and Vassana Netweera
Background: This study aims to investigate the stability of Zanthoxylum limonella Alston. seed (ZL) at various storage temperatures and anti-inflammatory activity of the topical oral gel (ZG) in a preclinical study.
Methods: The seed was stored in 2 different conditions: accelerated condition (50 °C, 70 °C and 90 °C) over 96 h and long-term condition (4 °C, 25 °C and 50 °C) over 6 months. Anti-inflammatory activity of the topical oral in rats was observed by using croton oil ear edema and oral punch wound healing.
Results: High storage temperature decreased the total phenolic content of ZL extract which the rate of degradation followed zero-order kinetic. In the long term condition, Z... view more»
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