Kirisci L Author
Subjects of specialization
Affiliation
contingency management ,cocaine dependence,addictive disorders,behavioral interventions
40 Bloomsbury Way Lower Ground Floor London, United Kingdom WC1A 2SE
Dr. Plebani has conducted research on the treatment of addictive disorders, including the evaluation of behavioral interventions for nicotine dependence, and pharmacotherapies for the treatment of cocaine dependence and alcohol dependence. His current research interests include investigating the mechanisms of action of promising pharmacotherapies in human laboratory studies, as well as clinical trials combining behavioral interventions such as contingency management with promising pharmacotherapies for cocaine, alcohol and opiate dependence.
Review Article Subscription
Author(s): Cornelius JR, Chung TA, Douaihy AB, Kirisci L, Glance J, Kmiec J, Wesesky MA, FitzGerald D and Salloum I
Background: Prior medication studies involving individuals with major depression in combination with an alcohol use disorder (MDD/AUD) have mainly focused on SSRI and tricyclic antidepressants, with generally ineffective results. Consequently, effective treatments for that common comorbid condition remain elusive. Mirtazapine is an antidepressant medicine with a unique pharmacological profile, whose effectiveness for treating noncomorbid depression reportedly may exceed that of SSRIs. Objective/Methods: We now review the published literature regarding the tolerability and efficacy of mirtazapine for the treatment of the depression and the pathological alcohol ingestion of individuals with co-occurring MDD/AUD, including a review of four of our own small stud... view moreĀ»