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Hindi Journal of Pharmaceutical Sciences & Emerging DrugsISSN: 2380-9477
Kouichi Nakagawaand VassanaNetweera Author
Subjects of specialization
Affiliation
Pharmacology, Pharmaceutical Sciences, Medicinal Chemistry, Drag reduction, Drug Therapy
School of Health Science, Mae Fah Luang University, Chiang Rai, 57100, Thailand.
Biography
Vassana Netweera; School of Health Science, Mae Fah Luang University, Chiang Rai, 57100, Thailand. He stated that, "The anti-inflammatory study suggests an effective dose of 10% of ZG which accelerated the wound size and reduced erythema compared to blank gel (p<0.001) and similar to FG (p=0.8) since the third day of treatment. The anti-inflammatory and wound healing activity of the ZG demonstrated re-epithelialized and wound closure, as supported by results of histopathology."
Publications
Research Article Open Access
Development of Topical Oral Anti-Inflammatory Gel Containing Zanthoxylum limonella seed Extracted: A Preclinical Study
Author(s): Aroonsri Priprem, Sucharat Limsitthichaikoon, Kouichi Nakagawa and Vassana Netweera
Background: This study aims to investigate the stability of Zanthoxylum limonella Alston. seed (ZL) at various storage temperatures and anti-inflammatory activity of the topical oral gel (ZG) in a preclinical study.
Methods: The seed was stored in 2 different conditions: accelerated condition (50 °C, 70 °C and 90 °C) over 96 h and long-term condition (4 °C, 25 °C and 50 °C) over 6 months. Anti-inflammatory activity of the topical oral in rats was observed by using croton oil ear edema and oral punch wound healing.
Results: High storage temperature decreased the total phenolic content of ZL extract which the rate of degradation followed zero-order kinetic. In the long term condition, Z... view more»
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