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Hindi Journal of Addictive Behaviors,Therapy & RehabilitationISSN: 2324-9005
Rice KC Author
Subjects of specialization
Affiliation
Dependence,Rhesus macaque, Intermittent access, CRH
Chemical Biology Research Branch, National Institute on Drug Abuse, 9800 Medical Center Drive, Bethesda, USA
Biography
Dr. Rice KC working as a Research Scientist in the department of Biosciences, FM University. He has area of research interest in the field of Biotechnology , Dependence, Rhesus macaque, Intermittent access, CRH
Publications
Research Article Open Access
Intermittent Access To Ethanol Induces Escalated Alcohol Consumption In Primates
Author(s): Lindell SG, Schwandt ML, Suomi SJ, Rice KC, Heilig M and Barr CS
Background: Escalation of voluntary alcohol drinking is characteristic of alcohol addiction and can be induced in rodents using intermittent access to alcohol. This model has been used to evaluate candidate therapeutics, but key systems involved in the transition into alcohol addiction, such as CRF, differ in their organization between rodents and primates. We examined the ability of an intermittent access schedule to induce escalation of voluntary alcohol drinking in non-human primates and used this model to assess the role of corticotropin releasing hormone (CRF) signaling in this process.
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