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+44 28 3718 0055Journal of Addictive Behaviors,Therapy & RehabilitationISSN: 2324-9005
Suomi SJ Author
Subjects of specialization
Affiliation
corticotropin releasing hormone ,alcohol addiction,therapeutics,CRFR1 blockade
Laboratory of Comparative Ethology, National Institutes of Health/National Institute of Child Health and Human Development, NIH Animal Center, USA
Biography
Dr. Suomi SJ working as a Research Scientist in the department of Laboratory of Comparative Ethology, National Institutes of Health/National Institute of Child Health and Human Development, NIH Animal Center, USA. He has area of research interest in the field of corticotropin releasing hormone alcohol addiction CRFR1 blockade therapeutics
Publications
Research Article Open Access
Intermittent Access To Ethanol Induces Escalated Alcohol Consumption In Primates
Author(s): Lindell SG, Schwandt ML, Suomi SJ, Rice KC, Heilig M and Barr CS
Background: Escalation of voluntary alcohol drinking is characteristic of alcohol addiction and can be induced in rodents using intermittent access to alcohol. This model has been used to evaluate candidate therapeutics, but key systems involved in the transition into alcohol addiction, such as CRF, differ in their organization between rodents and primates. We examined the ability of an intermittent access schedule to induce escalation of voluntary alcohol drinking in non-human primates and used this model to assess the role of corticotropin releasing hormone (CRF) signaling in this process.
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